Download GTU B.Pharma 2018 Summer 3rd Sem Pharmaceutical Engineering Ii Question Paper

Download GTU (Gujarat Technological University) B.Pharma (Bachelor of Pharmacy) 2018 Summer 3rd Sem Pharmaceutical Engineering Ii Previous Question Paper

Seat No.: _____ Enrolment No.______



GUJARAT TECHNOLOGICAL UNIVERSITY
B. Pharm. - SEMESTER?3 ? EXAMINATION ? SUMMER -2018
Subject code: 230002
Date: 02/05/2018
Subject Name: Pharmaceutical Engineering II
Time: 02:30 PM TO 05:30 PM
Total Marks: 80

Instructions:
1. Attempt any five questions.
2. Make suitable assumptions wherever necessary.
3. Figures to the right indicate full marks.

Q.1
(a) Discuss the regulatory requirements of content uniformity as per
06
USP and European Pharmacopoeia.

(b) Enumerate sampling techniques for content uniformity.
05

(c) Define content uniformity. Enumerate significance of content
05
uniformity.
Q.2
(a) Enumerate and explain different techniques used for improvement of 06
powder flow.

(b) Define Carr's Index and Hausner's ratio with their pharmacopoeial
05
specifications.

(c) Discuss the various factors affecting powder and granule flow.
05
Q.3
(a) Define Control chart. Enumerate different types of control charts
06
and discuss any one.

(b) Discuss the elements of Control charts.
05

(c) Enumerate Control charts for attributes and explain c chart.
05
Q.4
(a) Define HME and explain its significance in Pharmaceutical
06
Industry.

(b) Define pellets. Enumerate various factors affecting pellets
05
properties.

(c) What is Eudragit? Explain its role in melt extrusion technology.
05
Q.5
(a) Explain the term supercritical fluid, critical temperature and critical
06
pressure with the help of a pressure temperature phase diagram.

(b) Name different techniques involved in micronization employing
05
Supercritical fluid as an antisolvent.

(c) Define and explain pharmaceutical application of inclusion complex. 05
Q. 6
(a) Explain the process of preparing Solid dispersion using supercritical
06
fluid.

(b) Write advantages and disadvantages of RESS process.
05

(c) Explain applications of supercritical fluid in extraction process.
05
Q.7
Write a note on following:


(a) Solid dispersion
06

(b) Screw extruder
05

(c) MCC in pelletization
05
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