Download Pharm D 4th Year 2014 Oct 383823 Biopharmaceutics And Pharmacokinetics Question Paper

Download Pharm-D (Doctor of Pharmacy) 4th Year (Fourth Year) 2014 Oct 383823 Biopharmaceutics And Pharmacokinetics Previous Question Paper

[LF 823] OCTOBER 2014 Sub. Code: 3823
DOCTOR OF PHARMACY (PHARM. D / POST BACCALAUREATE)
DEGREE EXAMINATION
(2009-2010 Regulation)
FOURTH YEAR
PAPER V ? BIOPHARMACEUTICS AND PHARMACOKINETICS
Q.P. Code: 383823
Time: Three Hours Maximum: 70 marks
Answer All questions
I. Elaborate on: (4 x 10 = 40)
1. Define absorption.
Explain briefly about different mechanisms of drug absorption.
2. Advantages, Criteria of urinary excretion data.
How will you find out elimination rate constant from the data?
3. Bioequivalence study protocol.
4. Multiple dosage regimens.
II. Write notes on: (6 x 5 = 30)
1. Partition theory and its modifications.
2. Blood Brain Barrier.
3. Significance of protein binding.
4. Carternary model.
5. Wagner Nelson Method.
6. Theophylline was administered to a patient at a dosing rate of 600 mg/day and
1200 mg/day. Respective steady state concentrations were 9.8 mg/L and 28.6mg/L.
Find out K
m
and V
max
. Determine the dosing rate to achieve steady state
concentration of 15 mg/L.

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