Download Pharm D 4th Year 2017 May 383823 Biopharmaceutics And Pharmacokinetics Question Paper

Download Pharm-D (Doctor of Pharmacy) 4th Year (Fourth Year) 2017 May 383823 Biopharmaceutics And Pharmacokinetics Previous Question Paper

[LK 823] MAY 2017 Sub. Code: 3823

PHARM. ?D? AND PHARM. ?D? (POST BACCALAUREATE)
DEGREE EXAMINATION
(2009-2010 Regulation)
FOURTH YEAR
PAPER V ? BIOPHARMACEUTICS AND PHARMACOKINETICS

Q.P. Code : 383823
Time : Three hours Maximum : 70 Marks

I. Elaborate on: (4 x 10 = 40)

1. Define drug absorption. Discuss the physiochemical factors influencing GI
absorption of a drug.

2. Explain briefly two compartmental open model extra Vascular Administration.

3. Explain in details about pharmacokinetic and pharmacodynamic parameters.

4. What are the major parameters studied in the urinary excretion data?

II. Write notes on: (6 x 5 = 30)

1. Measurement of bioavailability.
2. Explain the mean residence time.
3. Volume of distribution.
4. Methods to enhance the bioavailability through enhancement of dissolution rate.
5. How can you graphically estimate K
m
and V
max
from steady state concentration?
6. Hepatic clearance and renal clearance.


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