Download RGUHS (Rajiv Gandhi University of Health Sciences) M.Pharma 2019 January (Master of Pharmacy) 1st Year (First Year) 1st Year 5132 Phytochemistry Previous Question Paper

Rajiv Gandhi University of Health Sciences
First Semester M. Pharm Degree Examination - JAN-2019
[Time: 3 Hours]
[Max. Marks: 75]
Phytochemistry
Q.P. CODE: 5132
Your answers should be specific to the questions asked.
Draw neat, labeled diagrams wherever necessary.
LONG ESSAY (Answer any Three)
3 X 10 = 30 Marks
1.
Describe the protocol for extraction for phytochemical screening of fresh and dry drugs. Explain
the tests for identification of various phytoconstituents.
2.
Explain different in-vitro and in-vivo screening methods for antidiabetic activity.
3.
Discuss the use of grafting and mutant strains for elucidation of biosynthetic pathways.
Describe the biosynthesis of ephedrine.
4.
Explain applications of LCMS and GCMS for phytochemical characterization of extracts.
SHORT ESSAY (Answer any Nine)
9 X 5 = 45 Marks
5.
Explain the biosynthesis of umbelliferone.
6.
Write a note on selection and optimization of lead anticancer compounds from natural sources
with suitable examples.
7.
Explain the isolation, purification and characterization of piperine.
8.
Explain different screening methods available for evaluation of antilithiatic activity.
9.
Explain the principle and applications of flash-column chromatography.
10.
Describe the biosynthesis of strychnine.
11.
Write the procedure for isolation, purification and identification of cucurbitacins.
12.
Explain different screening methods for antiviral activity.
13.
Substantiate herbs as potential source for drug discovery.
14.
Write the importance of HPTLC in herbal analysis.
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