Rajiv Gandhi University of Health Sciences

First Year M. Pharm Degree Examination

[Time: 3 Hours] [Max. Marks: 100]

Bioprocess Technology

(RS 2 & RS 3)

Q.P. CODE: 9313

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Your answers should be specific to the questions asked

Draw neat labeled diagrams wherever necessary

LONG ESSAY (Answer any FOUR) 4 X 25 = 100 Marks

1. Describe the effect of aeration, agitation and mass transfer in fermentation equipment. (25)
2. Discuss the rheology of fermentation systems and its importance in fermenter operation. (12+13 =25)
3. Short note on:
   1. Enzymatic assays

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   2. Bioautographic technique
   3. Disintegration
   (9 + 8 + 8=25)
4. Explain about the overview of economics in general fermentation process (12+13 = 25)
5. Discuss all the aspects of Isolation and purification of fermentation and biological products. (13+10+5 = 25)

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6. Explain the following terms:
   1. Michaelis - menten constant
   2. Effect of temperature on reaction rate
   3. Thermal death of microorganism
   (9 + 8 + 8=25)

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