Download RGUHS (Rajiv Gandhi University of Health Sciences) M.Pharma 2019 January (Master of Pharmacy) 1st Year (First Year) 1st Year Advanced Pharmacology And Toxicology Paper II Rs2 And Rs3 Previous Question Paper

Rajiv Gandhi University of Health Sciences
First Year M.Pharm Degree Examination - JAN-2019
[Time: 3 Hours]
[Max. Marks: 100]
ADVANCED PHARMACOLOGY AND TOXICOLOGY
PAPER II
(RS2 & RS3)
Q.P. CODE : 9242
Your answers should be specific to the questions asked.
Draw neat labeled diagrams wherever necessary.
LONG ESSAY (Answer any TWO)
2 X 20 = 40 Marks
1.
a. Define and Classify the receptors.
b. Explain in detail G protein coupled receptors.
c. Write a note on drugs acting on GABA receptors.
2.
a. Classify with examples antihypertensive drugs.
b. Discuss the therapeutic role of calcium channel blockers.
c. Discuss the role of local anesthetics in arrhythmia.
3.
a. Immunomodulators
b. Discuss various invivo and invitro carcinogenicity studies.
c. Explain the mechanism of multi drug resistance (MDR).
SHORT ESSAY (Answer any FIVE)
5 X 10 = 50 Marks
4.
Discuss the role of Nitric oxide as signaling molecule.
5.
Write a note on bradykinin.
6.
Discuss about various insulin preparations.
7.
Discuss Pharmacotherapy of Rheumatoid arthritis.
8.
Discuss female reproductive toxicity.
9.
Discuss chemoprophylaxis of tuberculosis
SHORT NOTES
2 X 5 = 10 Marks
10.
Oxygen free radicals
11.
Mechanism of action of digitoxin
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