Download RGUHS (Rajiv Gandhi University of Health Sciences) M.Pharma 2019 January (Master of Pharmacy) 1st Year (First Year) 2nd Year 5149 Advanced Instrumental Analysis Previous Question Paper

Rajiv Gandhi University of Health Sciences
Second Semester M. Pharm Degree Examination - JAN-2019
[Time: 3 Hours]
[Max. Marks: 75]
Advanced Instrumental Analysis
Q.P. CODE: 5149
Your answers should be specific to the questions asked.
Draw neat, labeled diagrams wherever necessary.
LONG ESSAY (Answer any Three)
3 X 10 = 30 Marks
1.
Describe the principle and instrumentation of ATR-IR.
2.
Explain the fragmentation patterns for alcohols and carbonyl compounds.
3.
Discuss the NOESY and COSY techniques of NMR spectroscopy.
4.
Write the principle, instrumentation and applications of ICP-MS.
SHORT ESSAY (Answer any Nine)
9 X 5 = 45 Marks
5.
Write the principle and applications of RIA.
6.
Discuss the Woodward - Fieser rule for , -carbonyl compounds.
7.
Write the principle and applications of super critical fluid chromatography.
8.
Explain the concept of cotton effect in ORD.
9.
Discuss the principle and instrumentation of TGA.
10.
Give the IR absorption frequencies and NMR peaks for the following compounds i) Ethyl methyl
ketone ii) Benzamide
11.
Explain Ring rule and isotope peak with suitable examples.
12.
Write a note on circular dichroism.
13.
Discuss the principle and applications of HPTLC.
14.
Identify the structure of an organic molecule consistent with the following spectra data
Molecular formula : C4H8O2
IR bands (cm-1) : 2981, 1752, 1390, 1250, 1055
NMR peaks () : 1.3 (triplet 3H), 2.1 (singlet 3H), 4.0 (quartet 2H)
Mass spectra peaks : 88, 61, 45, 43
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