Download RGUHS (Rajiv Gandhi University of Health Sciences) M.Pharma 2014 November (Master of Pharmacy) 1st Year 9349 Advanced Pharmacology And Toxicology Revised Scheme 4 Previous Question Paper

Rajiv Gandhi University of Health Sciences
First Year M. Pharm Degree Examination - Oct/Nov 2014
[Time: 3 Hours]
[Max. Marks: 100]
Advanced Pharmacology and Toxicology
(Revised Scheme 4)
Q.P. CODE: 9349
Your answers should be specific to the questions asked.
Draw neat, labeled diagrams wherever necessary.
LONG ESSAY (Answer any TWO)
2 X 20 = 40 Marks
1.
Enumerate various cell surface receptor families and explain the transduction pathway involved
in ion channel receptors and tyrosine kinase linked receptors.
2.
Explain pathophysiology and pharmacotherapy of Parkinson's and Alzheimer's disease. (10+10)
3.
What is mutagenicity? Enlist and explain various mutagenicity studies.
(2+18)
SHORT ESSAY (Answer any FIVE)
5 X 10 = 50 Marks
4.
Explain the pathogenesis of cardiac arrhythmias and write the pharmacology of any one drug
used for treatment of arrhythmias.
(4+6)
5.
Explain the role of neurotransmitters as signaling molecules with examples.
6.
Explain biosynthesis, physiological roles of 5-hydroxy tryptamine.
(4+6)
7.
Explain the principles and methods involved in male reproductive toxicity studies.
(5+5)
8.
Write a note on pharmacotherapy and critical analysis of rational use of drugs for COPD. (7+3)
9.
Explain cAMP as intracellular signal transduction secondary messenger.
SHORT NOTES
2 X 5 = 10 Marks
10.
Explain the pharmacotherapy of congestive heart failure.
11.
Explain the generation and actions of cytokines.
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