Download RGUHS (Rajiv Gandhi University of Health Sciences) M.Pharma 2013 May (Master of Pharmacy) 1st Year 9202 Advanced Organic Chemistry Rs 2 And Rs 3 Previous Question Paper

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Rajiv Gandhi University of Health Sciences
First Year M.Pharm Degree Examination ? May 2013
[Time: 3 Hours]
[Max. Marks: 100]
ADVANCED ORGANIC CHEMISTRY
(RS 2 & RS 3)
Q.P. CODE: 9202
Your answers should be specific to the questions asked.
Draw neat labeled diagrams wherever necessary. Answer all questions
LONG ESSAY (Answer any TWO)
2 X 20 = 40 Marks
1.
a) Discuss the stereochemistry of Steroids
b) Discuss the chemistry of tetrazole nucleus
2.
a) Describe the method of preparation and synthetic application of aceto acetic ester
b) Explain the mechanism of elimination reaction with examples
3.
Outline the scheme for the synthesis and chemical properties of some pharmaceutical
applications of.
a) Pyrimidies b) Dibenzapines c) Isoxazole
SHORT ESSAY (Answer any FIVE)
5 X 10 = 50 Marks
4.
Describe the concepts of retrosynthesis with examples.
5.
Discuss the synthesis and chemistry of quinoline ring and give some drug molecules having
that basic ring structure.
6.
Describe different types of chemical bonds and their properties
7.
Outline the mechanism of Friedle crafts acylation and alkylation with examples.
8.
Discuss the chemical nature of free radical and carbenes
9.
Describe the reaction mechanism and the reagents involved in oxidation and reduction
reactions
SHORT NOTES
2 X 5 = 10 Marks
10.
Microwave irradiation techniques in the synthesis of drugs with examples.
11.
Hydrogenation reactions with heterogenous catalysts
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