Download RGUHS (Rajiv Gandhi University of Health Sciences) M.Pharma 2012 November (Master of Pharmacy) 1st Year 9222 Pharmaceutical And Cosmetic Analysis Rs 2 And Rs 3 Previous Question Paper

9222_2012_2_S203
Rajiv Gandhi University of Health Sciences
]First Year M.Pharm Degree Examination ? Nov 2012

[Time: 3 Hours]
[Max. Marks: 100]
PHARMACEUTICAL AND COSMETIC ANALYSIS

(RS 2 & RS 3)

Q.P. CODE: 9222
Your answers should be specific to the questions asked.
Draw neat labeled diagrams wherever necessary. Answer all questions
LONG ESSAY (Answer any TWO)
2 X 20 = 40 Marks
1. (a) Write the preparation, standardization and application of karl ? Fischer reagent
(b) Explain dead stop end point technique in amperometry
2. (a) Write about sodium nitrite titrations with examples
(b) Explain theory of acid ? base titrations
3. (a) Discuss the quality control parameters of secondary packing materials used in pharmaceuticals
(b) Explain quality control of dental products
SHORT ESSAY (Answer any FIVE)
5 X 10 = 50 Marks
4. What are ligands and the types of ligands explain back titrations with edta sodium
5. Discuss the principal and application of potentiometry
6. What are Hair care products? How do they differ from skin care products
7. Add a detail note on estimation of weakly acidic substances by non ? aqueous titrations
8. Write notes on Metal ? ion indicators
9. Explain quality control of crude drugs
SHORT NOTES
2 X 5 = 10 Marks
10. What are primary and secondary standards, give examples, what are the properties of an ideal
primary standards
11. What are colour make up preparations
* * * * *

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9223_2012_2_S204
Rajiv Gandhi University of Health Sciences
First Year M. Pharm Degree Examination ? Nov 2012

[Time: 3 Hours]
[Max. Marks: 100]
INSTRUMENTAL METHODS OF ANALYSIS
PAPER III
(RS 2 & RS 3)

Q.P. CODE: 9223
Your answers should be specific to the questions asked.
Draw neat labeled diagrams wherever necessary. Answer all questions

LONG ESSAY (Answer any TWO)
2 X 20 = 40 Marks
1.
How do turbidimetry and nephelometry differ in their technique? With the help of sketches
explain their instrumentation. What are their applications?
2.
Give the theory of fluorescence. Describe the components of a typical fluorimeter. Write the
methods of assay of any two drugs involving fluorimetry
3.
What is the principle of colorimetric estimation of drugs? Giving examples describe the
methodlolgy of assay of any three importance colorimetric reagents
SHORT ESSAY (Answer any FIVE)
5 X 10 = 50 Marks
4.
Name a few analgesics drugs and write down the methods of assays of any two of them
5.
Give the principles of any three methods available for estimation of alkaloidal drugs
6.
How are drugs containing carboxylic acid and methoxyl groups estimated give examples
7.
Explain how F C and PDAB reagents are useful as chromogenic reagents
8.
With the help of a sketch, describe a flame photometer
9.
Write about radiochemical methods of analysis
SHORT NOTES
2 X 5 = 10 Marks
10. How do you determine the particle size of a drug powder
11. What is the application of Carr ? price reagent? Explain with relevant example
* * * * *

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9224_2012_2_S201
Rajiv Gandhi University of Health Sciences
First Year M.Pharm Degree Examination ? Nov 2012

[Time: 3 Hours]
[Max. Marks: 100]
CHEMICAL AND BIOLOGICAL EVALUATION
PAPER IV
(RS 2 & RS 3)

Q.P. CODE: 9224
Your answers should be specific to the questions asked.
Draw neat labeled diagrams wherever necessary. Answer all questions

LONG ESSAY (Answer any TWO)
2 X 20 = 40 Marks
1.
Discuss cleaning and personnel validation of pharmaceutical factory
2.
Elaborate applications of computer in quality control laboratory
3.
Discuss the microbial assay of ? Lactam antibiotics
SHORT ESSAY (Answer any FIVE)
5 X 10 = 50 Marks
4.
Discuss the principal and procedure of the assay of oxytocin
5.
Highlight pyrogens chemistry and properties
6.
Explain the various chemical tests carried out to assess the quality of potable water
7.
Write notes on biological assay of plague vaccine
8.
Enumerate the salient features of good laboratory practices
9.
Discuss warehouse and vendor audit
SHORT NOTES
2 X 5 = 10 Marks
10. What is sterility testing and interpretation
11. Define validation and classify them
* * * * *

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• 9222_2012_2_S203.doc
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• 9223_2012_2_S204.doc
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• 9224_2012_2_S201.doc
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