Download PTU (I.K.Gujral Punjab Technical University (IKGPTU)) B-Tech (Bachelor of Technology) BT-Bio Technology 2020 December 5th Sem 70506 Bioinformatics Previous Question Paper
Roll No.
Total No. of Pages :02
Total No. of Questions : 18
B.Tech. (BT) (2012 to 2017) (Sem.?5)
BIOINFORMATICS
Subject Code : BTBT-505
M.Code : 70506
Time : 3 Hrs. Max. Marks : 60
INST RUCT IONS T O CANDIDAT ES :
1 .
SECT ION-A is COMPULSORY cons is ting of TEN questions carrying TWO marks
each.
2 .
SECT ION-B c ontains F IVE questions c arrying FIVE marks eac h and s tud ents
have to atte mpt any FOUR q ues tions.
3 .
SECT ION-C contains THREE questions carrying T EN marks e ach and s tudents
have to atte mpt any T WO questio ns.
SECTION-A
Answer briefly :
1.
NCBI
2.
Sequin
3.
PRINTS
4.
PHI-BLAST
5.
SWISS-PROT
6.
Jukes-Cantor model
7.
MMDB
8.
Neighbor-Joining method
9.
SCOP
10. Ramachandran plot
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SECTION-B
11. Briefly describe any three secondary protein databases.
12. Briefly describe about PDB.
13. What are PAM and BLOSUM matrices? Describe their importance.
14. What are molecular markers? Write a note on Rasmol.
15. What is T-COFFEE? Describe about its approach in multiple sequence alignment.
SECTION-C
16. Describe the prediction of protein structure by using threading method.
17. Describe various methods used in phylogenetic tree constructions and their importance.
18. Align the following sequences by using Smith and Waterman algorithm.
seq 1: ATTCGATCC, seq 2: ACGAT (Use +1 for match and -2 for mismatch and -3 for
gap penalty).
NOTE : Disclosure of Identity by writing Mobile No. or Making of passing request on any
page of Answer Sheet will lead to UMC against the Student.
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This post was last modified on 13 February 2021