Download MBBS TMU 2nd Year 2015 MBS201A Pathology I Question Paper

Download MBBS (Bachelor of Medicine, Bachelor of Surgery) TMU (Teerthanker Mahaveer University) Second Year (2nd Year) 2015 MBS201A Pathology I Previous Question Paper

MBBS II (Second) Professional Examination 2014-15

Course Code: MBS201

Paper ID: 0322401

Pathology-I

Time: 2 Hours 40 Minutes

Max Marks: 30

Note: Attempt all questions. Draw proper diagrams to support

your answer.

Part `B'

1.

Describe Reversible and Irreversible injury. (7)


2.

A 70 years old man with complaint of severe backache was
found to have multiple punched out lytic lesion on X-ray in
skull and lumbar vertebrae.

a)

What is the diagnosis? (1)

b)

Describe all investigations to confirm diagnosis. (2)

c)

Draw labelled diagram of Bone marrow findings. (2)

d)

Write note on Bence Jones proteins. (2)

3.

Write short notes: (2x4=8)

a)

Pathogenesis of Septic Shock

b)

Tumor Markers

c)

Pathogenesis of AIDS

d)

Hypertrophy


4.

Describe briefly: (2x4=8)

a)

Sickle Cell Anemia

b)

CML.

c)

Draw well labelled diagram of peripheral smear picture of
megaloblastic anemia.

d)

Haemophilia

MBBS II (Second) Professional Examination 2014-15

Roll No.

Student's Name



Student's Signature

Invigilator's Signature



Course Code: MBS201



Paper ID: 0322403

Pathology-I

Part `A'



Time: 20 Minutes

Max Marks: 10

Note: 1. Attempt all questions and return this part of the question paper to the invigilator after 20 Minutes.
2. Please tick () correct one only. Cutting, overwriting or any other marking are not allowed.
3. For answering please use Ball- pen only.


c)

Megaloblastic anemia

Q.1

Hyperplasia is a type of:

d)

CML

a)

Cell aging

b)

Cellular adaptation

Q.10 Type of anemia seen in -Thalassemia is:

c)

Cell injury

a)

Normocytic normochromic

d)

Carcinoma

b)

Macrocytic normochromic

c)

Microcytic hypochromic

Q.2

Transplant rejection is an example of which

d) Normocytic hypochromic

type of hypersensitivity:



a) I

b) II

Q.11 The antigen presenting cells present in skin

c) III

d) IV

are called:
a)

Langher cells

Q.3

Which of the following is a wear and tear

b)

Langerhan's cell

pigment:

c)

Paneth cell

a)

Lipofuscin

b)

Melanin

d)

Littoral cell

c)

Hemosiderin d)

Bilirubin

P.T.O.
Q.12 Syphilis is caused by:

Q.4.

Schilling test is used in the diagnosis of:

a)

T palladium

a)

Thalassemia

b)

P. Ovale

b)

Multiple Myeloma

c)

M. pylori

c)

Hereditary spherocytosis

d)

M. leprae

d)

Megaloblastic Anaemia

Q.13 All are features of ITP Except:

Q.5

Special histo chemical attain for staining

a)

an



autoimmune



disorder,

amyloid is:

characterized by formation of anti

a)

Von Kossa

platelets antibodies

b)

Masson fontana

b)

Female preponderance

c)

Congo red

c)

Spleenonegaly is common in

d)

Veerroeff stain

primary ITP

Q.6

All of the enzymes are involved in free

d)

Patients respond to steroid

radical scavenger reactions Except:

Q.14 A 60 yrs old male present with backache .

a)

Catalase

Routine hematological investigation

b)

Superocide dismutase

revealed Rouleaux formation in smear &

c)

Creatine phophokinase

raised ESR. X- ray skull revealed lytic
lesion in skull. The most likely diagnosis is:

d)

Glutathione peroxidase

a)

Plasma cell myeloma

Q.7

Which of the following vitamins are

b)

B-cell lymphoma

involved in formation of collagen:

c)

T- cell lymphoma

a)

Vitamin A

d)

Metastatic carcinome

b)

Vitamin B

Q.15 Most common cause of fat embolism is:

c)

Vitamin C

a)

Splenic rupture

d)

Vitamin D

b)

Fracture neck of femur

Q.8

AML ? M3 is characterized by:

c)

Liposarcoma

a)

Translocation 4,11

d)

D. I. C.

b)

Translocation 9, 22

Q.16 An example of Co-dominance is:

c)

Translocation 9, 11

a)

Sickle cell Anaemia

d) Translocation 15, 17

b)

Hemolytic anemia

Q.9

Auto Splenectomy is seen in:

c)

Blood group antigen

a)

Thalassemia

d)

Spermatic antigen

b)

Sickle cell anemia

Q.17 The main bactericidal substance of

eosinophils is:
a)

BPI

b)

Major Basic protein

c)

Lysosome

d)

Lactoferrin

Q.18 The predominant cells within 24 ? 48 hours

in acute inflammation are:
a)

Neutrophils

b)

Lymphocytes

c)

Eosinophils

d)

Monocytes

Q.19 Precancerous changes are suggested by:



a)

Aplasia

b)

Hyperplasia

c)

Dysplasia

d)

Hypertrophy

Q.20

All are example of macrocytic anemia
except.
a)

Pernicious anemia

b)

Megaloblastic anemia

c)

Sickle cell anemia

d)

Folic acid deficiency