Download MBBS TMU 2nd Year 2017 MBS203 Pharmacology II Question Paper

Download MBBS (Bachelor of Medicine, Bachelor of Surgery) TMU (Teerthanker Mahaveer University) Second Year (2nd Year) 2017 MBS203 Pharmacology II Previous Question Paper

MBBS II (Second) Professional Examination 2016-17


Course Code:MBS203

Paper ID: 0322412



Pharmacology-II


Time: 2 Hours 40 Minutes



Max Marks: 30


Note: Attempt all questions. Draw proper diagrams to support


your answer.









Part `B'


1.

Write short notes on the following: (2x4=8)

a) Corticosteroids
b) Oral contraceptives
c) DPP-IV inhibitors
d) Bisphosphonates

2.

Explain the pharmacological basis of following: (2x4=8)

a) 5-reductase inhibitors in Benign Prostatic Hypertrophy

(BPH)

b) Hormone replacement therapy in Post menopausal women
c) Low dose Aspirin as an antiplatelet
d) Combination of Penicillin & Gentamicin

3.

A 60 year old patients presented in emergency with pain in
chest associated with sweating and uneasiness. On
examination ST elevation was found in ECG. Patient was
diagnosed a case of Myocardial Infarction (MI). Answer
the following: (7)

a) Classify Antianginal drugs
b) Write MOA of Nitrates, uses and ADRs
c) Treatment of MI
d) Post MI treatment and advice

4.

Classify antiretroviral drugs. Explain the guidelines for
Highly Active Antiretroviral Therapy (HAART). Write a
short note on Post exposure prophylaxis in HIV positive
patient. (7)



MBBS II (Second) Professional Examination 2016-17



Roll No.















Student's Name







Student's Signature











Invigilator's Signature










Course Code:MBS203











Paper ID: 0322412

Pharmacology-II



Part `A'




Time: 20 Minutes

















Max Marks: 10


Note: 1. Attempt all questions and return this part of the question paper to the invigilator after 20 Minutes.
2. Please tick () correct one only. Cutting, overwriting or any other marking are not allowed.
3. For answering please use Ball- pen only.




Q.1

Thiazides cause all except:

Q.6

All of the following statements regarding

a)

Hyperglycemia



verapamil are true Except:

b)

Increased calcium excretion

a)

It blocks L-type calcium channels

c)

Hyperuricemia

b)

It increases heart rate

d)

Useful in congestive heart failure

c)

It relaxes coronary artery smooth



muscle

Q.2

The primary indication of tamoxiphen

d)

It depresses cardiac contractility

citrate is:





a. Female infertility

Q.7

Select the drug which is an `inodilator'

b. Endometrial carcinoma

beneficial in refractory congestive heart

c. Carcinoma breast

failure:

d. Endometriosis

a)

Nicorandil





b)

Amiodarone

Q.3

Mifepristone (RU-486) is:

c)

Amrinone

a)

Antiprogestin

d)

Carvedilol

b)

Antiandrogen



c)

Antiestrogen

Q.8

Which of the following antiplatelate drugs

d)

Enalapril

is not given by oral route:



a)

Aspirin

Q.4. HMG-CoA reductase inhibitor is:

b)

Clopidogrel



a)

Rosuvastatin

c)

Ticlopidine



b)

Clofibrate

d)

Abciximab

c)

Gemfibrozil







d)

Enalapril

Q.9

Aminoglycosides have the following



unwanted effects:

Q.5

Antidote for heparin is:

a)

Pancytopenia

a)

Vit. K

b)

Hepatotoxicity

b)

Protamine

c)

Ototoxicity, nephrotoxicity

c)

EDTA

d)

Irritation of gastrointestinal mucosa

d)

Desferioxamine













P.T.O



Q.10 The primary route of administration of

b)

Warfarin

insulin is:

c)

Heparin

a)

Intradermal



d)

Phenindione

b)

Subcutaneous



c)

Intramuscular

Q.18 MOA of penicillin is:

d

Intravenous



a)

Inhibits cell membrane synthesis





b)

Inhibits cell wall synthesis

Q.11 Rifampin has the following unwanted



c)

Inhibits mitochondrial function

effect:



d)

Inhibits protein synthesis

a)

Dizziness, headache





b)

Loss of hair

Q.19 Which

is

not

a

3rd

generation

c)

Flu-like syndrome

cephalosporin:

d)

Hyperuricemia



a)

Ceftriaxone





b)

Cephalexin

Q.12 Which of the following antianginal agents



c)

Cefotaxime

is a beta blocker:



d)

Cefoperzone



a)

Dipyridamole



b)

Verapamil

Q.20 Chloroquine in malaria acts on:



c)

Atenolol



a)

Erythrocytic cycle

d)

Minoxidil



b)

Exo-erythrocytic cycle





c)

Liver

Q.13 The drug which should not be administered

d)

Tissue schizonts

to patients taking potassium supplements:



a)

Hydrochlorothiazide

b)

Spironolactone

c)

Furosemide

d)

Neither of the above


Q.14 The daily dose of estrogen for hormone

replacement therapy in postmenopausal
women is:
a)

Same as for contraception

b)

Higher than that for contraception

c)

Lower than that for contraception

d)

Variable depending on the age of
the women


Q.15 Tick the drug, inhibiting viral reverse

transcriptase:
a)

Zidovudine

b)

Vidarabine

c)

Rimantadine

d)

Gancyclovir



Q.16 Which of the following vitamins is given

with Isoniazid in the treatment of
tuberculosis:
a)

Nicotinic acid

b)

Riboflavin

c)

Pyridoxine

d)

Ascorbic acid


Q.17 Which is not an oral anti-coagulant:


a)

Dicumarol