Download DNB 2016 Dec BIOCHEMISTRY P I Question Paper

Download Diplomate of National Board (DNB) 2016 Dec BIOCHEMISTRY P I Previous Question Paper

FINAL EXAM NATIONAL BOARD OF EXAMINATIONS
DECEMBER 2016
POSSESSION / USE OF CELL PHONES OR ANY SUCH ELECTRONIC GADGETS IS NOT PERMITTED INSIDE THE
EXAMINATION HALL.
BIOCHEMISTRY

PAPER ? I
BIO/D/16/03/I
Time : 3 hours
Max. Marks : 100

Important instructions:

? Attempt all questions in order.
? Each question carries 10 marks.
? Read the question carefully and answer to the point neatly and legibly.
? Do not leave any blank pages between two answers.
? Indicate the question number correctly for the answer in the margin space.
? Answer all the parts of a single question together.
? Start the answer to a question on a fresh page or leave adequate space between two answers.
? Draw table/diagrams/flowcharts wherever appropriate.
Write short notes on:

1. Write the step(s) with the reaction(s) used in the in-vitro synthesis of a
peptide having sequence ?ala-cys-glu?.

10
2. a) Classify glycerolipids.
b) Structure, functions and clinical significance of glycerolipids.

1+(3+3+3)
3. a) List five heteropolysaccharides.
b) Mention their structures and diseases associated with their defective
metabolism.

2.5+(2.5+5)
4. a) Define prenatal fetal screening of diseases.
b) List biochemical test(s) performed for fetal screening.
c) Mention how those tests are interpreted?

2+2+6
5. a) How are glomerular, tubular and endocrine functions of kidney assessed
by biochemical investigation(s)?
b) How is adequacy of hemodialysis assessed by laboratory tests?

6+4
6. Define and write the use(s) of:
a) Abzymes.
b) Isoform of enzymes.
c) Isoenzymes.
d) Ribozymes.

2.5x4
7. List the Westgard rejection rules. Add a note on ?external quality control?.

7+3
8. a) How is reference range of a laboratory parameter established?
b) Define diagnostic window of laboratory parameter. Compare diagnostic
window of CK-MB and myoglobin for acute myocardial infarction.

5+5
9. a) Define ?null hypothesis?.
b) List the test(s) of comparison used to reject null hypothesis.
c) What does ?p value? signify?

2+5+3
10. a) How is correlation analysis performed for a nonparametric data?
b) Compare and contrast ?correlation analysis? with ?regression analysis?.
6+4
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