Download RTMNU B.Pharma 3rd Semester 2016 Summer Pharmacology 1 Question Paper

Download RTMNU (Rashtrasant Tukadoji Maharaj Nagpur University) B.Pharma (Bachelor of Pharmacy) 3rd Semester 2016 Summer Pharmacology 1 Question Paper

TKN/KS/16 ?6984
Third Semester Examination for the Degree
of Bachelor of Pharmacy
PHARMACOLOGY ? 1
3-T-4
Time : Three Hours] [MaX. Marks : 80
N. B. :(1) Question No.1 is Compulsory.
(2) Solve any Four questions from the remaining.
(3) Draw neat labeled diagram wherever neces?
sary.
1. Solve any Five.
(21) Explain neurohumoral transmission.
(b) Explain clinical significance of (x?adrenergic
blocker.
(c) Justify the combination of adrenaline and lidocaine.
(d) Explain Dale vasomotor reversal phenomenon.
e DCSCF1bC the phenomenon Of syner 18m and
g
potentiation W1th suitable examples.
(1) Write a brief note on orphan receptors.
(g) Give clinical signi?cance of Antimuscarinc agents.
5 X4 = 20
2. Explain different phases of bio?transformation along
with suitable examples. 15
TKN/KS/16 ? 6984 Contd.
3. Explain different types of receptors in detail. Describe
dif?cult factors affecting drug receptor interaction. 15
4. Give classi?cation of Anti?cholinesterase?s. Describe their
mechanism of action, adverse effect and clinical
indications. 15
5. Give classi?cation and describe detail pharmacological
pro?le of B-blockers with their speci?c clinical indication.
15
6. Give classification and explain mechanism of action,
Adverse effect and therapeutic uses of ganglionic
blockers and neuromuscular blocking agents. 15
7. Solve any Three of the following :?
(a) Explain the phenomenon of competative
antagonism with suitable examples.
(b) Describe symptoms and treatment of organo?
phosphate poisoning.
(0) Give detail guidelines for therapeutic intervention
of Myastania Gravis.
((1) Describe various factors affecting drug distribution
and explain its clinical signi?cance.
3 X 5 = 15
TKN/KS/16? 6984 2 530