Download University of Jaffna (University of Sri Lanka) MBBS (Bachelor of Medicine and Bachelor of Surgery) 2012 January Pharmacology Paper II Previous Question Paper

UNIVERSITY OF JAFFNA, SRI LANKA
SECOND EXAMINATION FOR MEDICAL DEGREES PART II (SECOND)
JANUARY 2012
Pharmacology - Paper II
Date: 02.02.2012.
Time: 02 hours
ANSWER ALL THE FOURQUESTIONS
I .
Explain the pharmacological basis for
1.1. using morphine in the immediate management of myocardial
infarction.
(40 Marks)
1.2. combining levodopa and carbidopa.
(30 Marks)
1.3. preferring low molecular heparins for the prophylaxis of
thromboembohism over unfractionated heparin.
(30 Marks)
2.
,
2.1. List the first-line antituberculous drugs.
(20 Marks)
2.2. Briefly describe the mechanism of action of each of the drug
mentioned above.
(40 Marks)
2.3. Mention the important adverse effects of the drugs mentioned in
2.1.
(20 Marks)
2.4. Outline the precautions you would take to prevent/ minimise the
adverse effects mentioned above.
(20 Marks)
3.
Write an account on the therapeutic applications of
3.1. aspirin.
(30 Marks)
3.2. benzodiazepines.
(30 Marks)
3.3. glucocorticoids.
(40 Marks)
4.
A 18 year old girl collapsed at the outpatient department after
receiving benzathine penicillin injection for rheumatic fever
prophylaxis. Her blood pressure was 80/60 mmHg and respiratory
system examination revealed stridor and wheeze. She was treated
for anaphylactic shock.
4.1. Explain the basis for the signs and symptoms of this patient.
(30 Marks)
4.2. List the drugs that are used to treat this patient.
(20 Marks)
4.3. Explain the rationale for using the drugs mentioned in 4.2. to treat
this patient.
(40 Marks)
4.4. Mention the alternative drugs that could be used for rheumatic fever
prophylaxis for this patient.
(10 Marks)
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