Download RGUHS M.Pharmacy First Year May 2016 9283 Biopharmaceutics And Pharmacokinetics Rs 2 And Rs 3 Question Paper

Download RGUHS (Rajiv Gandhi University of Health Sciences) M Pharma (Master of Pharmacy) First Year (1st Year) May 2016 9283 Biopharmaceutics And Pharmacokinetics Rs 2 And Rs 3 Question Paper.

Rajiv Gandhi University of Health Sciences
First Year M.Pharm Degree Examination - May 2016
[Time: 3 Hours] [Max. Marks: 100]
BIOPHARMACEUTICS AND PHARMACOKINETICS
(RS 2 & RS 3)
Q.P. CODE : 9283
Your answers should be specific to the questions asked.
Draw neat labeled diagrams wherever necessary.

LONG ESSAY (Answer any TWO) 2 X 20 = 40 Marks
1. Explain various factors affecting biotransformation of drugs.
2. Define Rate of Elimination and Clearance. Explain Non-Renal Clearance in detail.
3. Explain in detail the application of pharmacokinetics in development of controlled release drug
delivery system.

SHORT ESSAY (Answer any FIVE) 5 X 10 = 50 Marks
4. Explain drug related factors affecting absorption of drug.
5. Explain significance of protein binding.
6. Deduce equation to obtain pharmacokinetic parameters of a drug administered by IV infusion
and body acting as single compartment.
7. Explain concept of loading dose and maintenance dose.
8. Write a note on in-vitro in-vivo correlation.
9. Why is, human serum albumin considered a versatile protein for drug binding?

SHORT NOTES 2 X 5 = 10 Marks
10. Individualization
11. Polar drugs such as penicillin normally do not cross BBB but do so in meningitis. Explain.

* * * * *
FirstRanker.com - FirstRanker's Choice