Download RGUHS (Rajiv Gandhi University of Health Sciences) M Pharma (Master of Pharmacy) First Year (1st Year) 2011 May 9201 Modern Pharmaceutical Analysis Question Paper.
Rajiv Gandhi University of Health Sciences
First Year M.Pharm Degree Examination ? May 2011
[Time: 3 Hours] [Max. Marks: 100]
MODERN PHARMACEUTICAL ANALYSIS
(RS 2 & RS 3)
Q.P. CODE: 9201
Your answers should be specific to the questions asked.
Draw neat labeled diagrams wherever necessary. Answer all questions
LONG ESSAY (Answer any TWO) 2 X 20 = 40 Marks
1. Define chromatography and classify chromatographic methods on mechanism of separation
with applications. Write a note on TLC preparation techniques, mobile phase, selection and
detection methods.
2. What is the principle involved in IR spectroscopy and give a brief outline of classical IR
instrumentation. Write a note on sample handling in IR spectroscopy. Add a note on qualitative
interpretion of IR spectras
3. Explain the phenomenon of optical rotation and circular dichroism. Giving a schematic diagram,
write about an ORD instrument. What are the application of ORD and CD?
SHORT ESSAY (Answer any FIVE) 5 X 10 = 50 Marks
4. Define octant rule and its application with examples.
5. Discuss the application of signal split and coupling constant data to interpretation pmr spectra?
6. Explain in brief about various detectors in gas chromatography.
7. Write about chemical ionization mass spectrometry. Add a note on relative abundances of
isotopes and their contribution to characteristic peaks?
8. Write about moving boundary electrophoresis and its applications
9. Give a note on zone electrophoresis and isotachophoresis?
SHORT NOTES 2 X 5 = 10 Marks
10. Woodward?s rule.
11. Shifts in uv spectra
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This post was last modified on 20 December 2019