Download PTU B.Tech 2020 March Biotechnology 5th Sem BTBT 505 Bioinformatics Question Paper

Download PTU (I.K. Gujral Punjab Technical University Jalandhar (IKGPTU) ) BE/BTech Bio-Technology (Biotechnology Engineering) 2020 March 5th Sem BTBT 505 Bioinformatics Previous Question Paper

1 | M-70506 (S2)-710
Roll No. Total No. of Pages :02
Total No. of Questions : 09
B.Tech.(BT) (2012 to 2017) (Sem.?5)
BIOINFORMATICS
Subject Code : BTBT-505
M.Code : 70506
Time : 3 Hrs. Max. Marks : 60
INSTRUCTIONS TO CANDIDATES :
1. SECTION-A is COMPULSORY consisting of TEN questions carrying TWO marks
each.
2. SECTION-B contains FIVE questions carrying FIVE marks each and students
have to attempt any FOUR questions.
3. SECTION-C contains THREE questions carrying TEN marks each and students
have to attempt any TWO questions.

SECTION-A
1. Answer briefly :
a. Sequence similarity vs. sequence identity
b. EMBL
c. Global alignment
d. Affine gap penalties
e. BIT score
f. Rasmol
g. COGS
h. Bootstrap
i. Entrez
j. Phylogram

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1 | M-70506 (S2)-710
Roll No. Total No. of Pages :02
Total No. of Questions : 09
B.Tech.(BT) (2012 to 2017) (Sem.?5)
BIOINFORMATICS
Subject Code : BTBT-505
M.Code : 70506
Time : 3 Hrs. Max. Marks : 60
INSTRUCTIONS TO CANDIDATES :
1. SECTION-A is COMPULSORY consisting of TEN questions carrying TWO marks
each.
2. SECTION-B contains FIVE questions carrying FIVE marks each and students
have to attempt any FOUR questions.
3. SECTION-C contains THREE questions carrying TEN marks each and students
have to attempt any TWO questions.

SECTION-A
1. Answer briefly :
a. Sequence similarity vs. sequence identity
b. EMBL
c. Global alignment
d. Affine gap penalties
e. BIT score
f. Rasmol
g. COGS
h. Bootstrap
i. Entrez
j. Phylogram

2 | M-70506 (S2)-710
SECTION-B
2. Write about the CATH database.
3. Describe the GOR method of protein secondary structure prediction.
4. Explain Smith-Waterman algorithm.
5. Describe any one multiple sequence alignment tool.
6. Differentiate between PAM and BLOSUM scoring matrices.

SECTION-C
7. Blast is used for database searching. Describe the BLAST algorithm and BLAST output.
8. Describe different bioinformatics methods of gene prediction. How prokaryotic gene
prediction tool is different from eukaryotic gene prediction tool?
9. Write the application of phylogenetic tree constructions. Construct the tree based on
given matrix using UPGMA method.
A B C D
A 0
B 7 0
C 6 8 0
D 11 13 10 0





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