Download MBBS 1st Year 2023 nOV 526056 Biochemistry Paper II Cbme MCQs Question Paper

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THE TAMIL NADU DR. M.G.R. MEDICAL UNIVERSITY
[MBBS 1123]
NOVEMBER 2023 Sub. Code :6056

M.B.B.S. DEGREE EXAMINATION
(For the candidates admitted from the Academic Year 2019-2020)

FIRST YEAR ? (CBME)
PAPER II ? BIOCHEMISTRY

Q.P. Code: 526056
Time: 30 Minutes


Maximum : 20 Marks
Answer All Questions

Choose one correct answer in the box provided in the Answer Script.
No overwriting should be done. Choice should be given in Capital Letters.
III. Multiple Choice Questions:



(20 x 1 = 20)

1. To which of the following structures in a typical molecule of tRNA is an
aminoacid attached?
A)Variable loop B) Anti Codon loop C) D ? loop D) CCA tail
2. Daily requirement of iodine for an adult is
A)15 ? 20 ?g B) 150 ? 200 ?g C) 300 ? 400 ?g D) 400 ? 500 ?g
3. All are inhibitors of RNA synthesis except
A) Rifampicin B) Puromycin C) Amanitin D) Actinomycin D
4. In prokaryotes DNA replication is inhibited by what drug?
A) Chloramphenicol B) Rifamycin C) Ciprofloxacin D) Streptomycin
5. Which immunoglobulin can cross placental barrier?
A) IgG B) IgM C) IgA D) IgD
6. Orotic aciduria is due to deficiency of which enzyme?
A) Carbamoyl phosphate synthetase II B) Aspartate transcarbomylase.
C) Dihydrooratase D) Orotatephophoribosyltransferase
7. All following are substrates for transmethylation reactions except
A) Guanidoacetic acid B) Choline C) Norepinephrine D) N acetylserotonin
8. Which is the radio isotope used for measuring nucleic acid synthesis?
A) 51 Cr B) 131 I C) 32 P D) 14 C
9. Wilson's disease is due to abnormal metabolism of following mineral
A) Manganese B) Copper C) Zinc D) Selenium
10. What is the most common environmental poison in India?
A) Aluminium B) Lead C) Mercury D) Arsenic
11. Which of the following test measure GFR accurately?
A) Creatinine clearance B) Urea clearance
C) Inulin clearance D) PAH clearance
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12. Emphysema is due to deficiency of which of the following protein?
A) C- Reactive protein B) Alpha ? 1 Antitrypsin.
C) Ceruloplasmin D) Alpha ? 2 Macroglobulin
13. Crigler ? Najjar syndrome is due to deficiency of which enzyme?
A) UDP ? Glucoronyltransferase B) Bilirubin reductase
C) Cytochrome oxidase D) Ferrochelatase
14. The pattern of inheritance shown by glucose-6-phosphate dehydrogenase deficiency is
A) Autosomal dominant B) Autosomal recessive.
C) X ? linked dominant D) X ? linked recessive.
15. Which of the following is the basis for the intestine specific expression of apolipoprotein
B ? 48 ?
A) DNA transposition B) RNA Alternative splicing
C) RNA editing D) RNA interference
16. Which of the following is true with regards to p53?
A) It is an oncogene B) It is an oncosuppressor gene
C) It is an inducer of heme synthesis D) It is deleted in mental retardation
17. Which of the following is the major intracellular mineral
A) Magnesium B) Potassium C) Sodium D) Calcium
18. Which of the following is an example of phase two detoxification?
A) Hydrolysis B) Conjugation C) Reduction D) Dealkylation
19. Among the following, all are hormones that act on cytosolic receptor except
A) Thyroxine B) Epinephrine C) Glucagon D) Insulin
20. Which of the following is not an emergency investigation?
A) Potassium B) Fasting glucose C) Creatinine D) Calcium
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[MBBS 1123]

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