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[MBBS 0524] MAY 2024 Sub. Code :6064
M.B.B.S. DEGREE EXAMINATION
(For the candidates admitted from the Academic Year 2019-2020)
SECOND PROFESSIONAL ? SUPPLEMENTARY (CBME)
PAPER II ? PATHOLOGY
Q.P. Code: 526064
Time: 20 Minutes Answer All Questions Maximum : 20 Marks
Choose one correct answer in the box provided in the Answer Script.
No overwriting should be done. Choice should be given in Capital Letters.
III. Multiple Choice Questions:
(20 x 1 = 20)
1. Post MI day 10 which enzyme is raised
A) CPK B) Troponin C) LDH D) Myoglobin
2. Which valve is most commonly involved in prosthetic valve endocarditis
A) Mitral valve B) Tricuspid valve C) Aortic valve D) Pulmonary valve
3. Most commonly affected age group in rheumatic fever
A) 15-25 years B) 25-35 years C) 5-15 years D) 35-45years
4. A 50 year old man presents to emergency department with chest pain and syncope.
Physician suspects coronary pathology. Coronary arteriography shows significant
atherosclerotic involvement of left anterior descending and circumflex arteries.
Which of the following provides major proliferative stimuli for the cellular
components of atherosclerotic plaques?
A) Neutrophils B) Eosinophils C) Platelets D) Erythrocytes
5. Endoscopic biopsy shows intraepithelial lymphocytes in all the following conditions except
A) Celiac disease B) Viral enteritis C) Giardiasis D) Campylobacter entercolitis
6. Angiodysplasia is most commonly seen in which part of colon
A) Cecum B) Transverse colon C) Sigmoid colon D) Rectum
7. A 20-year-old man is healthy but has a family history of colon cancer. He undergoes
colonoscopy and there are over 200 tubular adenomas ranging in size
from 0.2 to 1 cm on gross inspection. Which of the following genetic diseases is
he most likely to have?
A) Hereditary non-polyposis colon carcinoma syndrome
B) PTEN-associated syndrome
C) Peutz-Jeghers syndrome
D) Adenomatous polyposis coli
8. A 25-year-old male presented with intermittent cramping abdominal pain, fever and
low-volume diarrhea. A colonoscopy reveals mucosal edema and patchy ulceration in the
ascending colon. Which of the following serological marker is positive in this case?
A) Perinuclear anti neutrophil cytoplasmic antibodies
B) Anti endomysial antibodies
C) Anti-Saccharomyces cerevisiae antibodies
D) Anti smooth muscle antibody
9. A patient with an elevated serum alpha fetoprotein undergoes resection of a liver
mass. The mass has the following features: crowded cells growing in thick
(4 or more cells) cords/plates, occasional mitoses, an absence of normal bile ducts,
and necrosis. Which is the MOST LIKELY diagnosis?
A) Hepatocellular adenoma B) Cholangiocarcinoma
C) Focal nodular hyperplasia D) Hepatocellular carcinoma
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10. On reviewing a liver biopsy specimen, the following features are identified: steatosis,
Mallory bodies, and acute inflammation. Which of the following is the MOST
LIKELY diagnosis?
A) Primary biliary cirrhosis B) Acetaminophen overdose
C) Herpetic hepatitis D) Alcohol-related liver disease
11. Which of the following statements BEST DESCRIBES genetic hemochromatosis?
A) Iron deficiency anemia develops from a mutation in the HFE gene
B) It is an autosomal dominant disorder that can lead to iron overload in the liver
and other organs
C) Patients homozygous for a mutant HFE allele absorb excessive quantities of
iron from the diet
D) Women typically manifest the disease earlier than men, who are protected by
higher androgen levels
12. Impaired hepatic blood flow in veno-occlusive disease is due to:
A) Thrombosis of the major hepatic veins B) Nodular regeneration of the parenchyma
C) Fibrous obliteration of terminal hepatic veins D) Fibrous obliteration of large bile ducts
13. Ovarian cyst lined by luteinized granulosa cells
A) Follicular cysts B) Cystic follicle C) Luteal cyst D) Serous cyst
14. A 45 year old female presented with bulky uterine mass. Histopathology shows
bizarre spindle cells with mitotic activity > 10/10Hpf. Which of the following is the
most likely diagnosis?
A) Leiomyoma B) Endometrial Stromal sarcoma
C) Leiomyosarcoma D) Malignant mixed mullerian tumour
15. Which of the following statement is true regarding serous carcinoma of endometrium
A) Endometrial hyperplasia is a risk factor B) Poor prognosis
C) Associated with MLH 1 mutation D) Low grade tumour
16. Identify the false statement regarding endometrial hyperplasia
A) Associated with obesity
B) Most common genetic alteration is MET mutation
C) atypical hyperplasia have more risk of malignancy
D) Presence of metaplastic epithelium is benign
17. An 18-year-old man complains of a subacute onset of knee pain. A radiograph
demonstrates an expansile, 10-cm mass arising within the proximal tibia with
associated lifting of the periosteum and linear radiating calcifications perpendicular to
the bone axis. This mass is concerning for which of the following?
A) Osteosarcoma B) Rheumatoid arthritis C) Bone fracture D) Osteoid osteoma
18. The presence of a bulky, polypoid, grape-like mass protruding from the vagina
of a 3-year-old girl should raise concern for which of the following?
A) Synovial sarcoma B) McCune-Albright syndrome
C) Ewing sarcoma D) Embryonal rhabdomyosarcoma
19. Which lesion is a palmar variant of fibromatosis characterized by an irregular, nodular
thickening of the palmar fascia?
A) Desmoid fibromatosis B) Peyronie disease
C) Dupuytren contracture D) Dermatofibroma
20. Osteomas of the jaw are associated with which syndrome?
A) McCune-Albright syndrome B) Down syndrome
C) Lesch-Nyhan syndrome D) Gardner syndrome
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[MBBS 0524]
This post was last modified on 30 November 2024