Download MBBS (Bachelor of Medicine, Bachelor of Surgery) TMU (Teerthanker Mahaveer University) First Year (1st Year) 2018 MBS103 Biochemistry I Previous Question Paper
MBBS I (First) Professional Examination 2017-18
Course Code: MBS103 Paper ID: 0322208
Biochemistry -I
Time: 2 Hours 40 Minutes
Max Marks: 40
Note: Attempt all questions. Draw proper diagrams to support
your answer.
Part `B'
1.
Discuss the metabolism of Phenylalanine in detail.
Enumerate the synthesis of different products obtained
from Phenylalanine/Tyrosine. (10)
2.
Explain the causes, clinical manifestations and laboratory
diagnosis of the following: (5+5)
a)
Type 2 Diabetes Mellitus
b)
Sickle-cell anemia
3.
Write in detail: (5+5)
a) Lipotropic Factors
b) Gout
4.
Describe the following: (5+5)
a) Metabolic changes during starvation
b) Factors affecting enzyme action
MBBS I (First) Professional Examination 2017-18
Roll No.
Student's Name
Student's Signature
Invigilator's Signature
Course Code:MBS103
Paper ID: 0322208
Biochemistry - I
Part `A'
Time: 20 Minutes
Max Marks: 10
Note: 1. Attempt all questions and return this part of the question paper to the invigilator after 20 Minutes.
2. Please tick () correct one only. Cutting, overwriting or any other marking are not allowed.
3. For answering please use Ball- pen only.
Q.1
Which of the following is an epimeric pair:
b)
Phospholipase A2
a)
Glucose & maltose
c)
Cyclo-oxygenase
b)
Glucose & Fructose
d) Lipo-oxygenase
c)
Glucose & mannose
d)
Glucose & ribose
Q.7
Primary structure of a protein is broken by:
a)
Heat
Q.2
G-proteins act as:
b)
Ammonium sulphate
a. Hormone carriers
c)
Pepsin
b. Hormone receptors
d)
All of the above
c. Signal transducers
d. Second messengers
Q.8
Which of the following nitrogenous base is
absent from DNA:
Q.3
Allopurinol is a competitive inhibitor of:
a)
Uracil
a)
Dihydrofolate reductase
b)
Thymine
b)
Xanthine oxidase
c)
Adenine
c)
Carbonic anhydrase
d)
Guanine
d)
Acetylcholinesterase
Q.9
Following myocardial infarction, the last
serum enzyme to return to normal is:
Q.4
Cyanide inhibits phosphorylation at:
a)
Creatine kinase
a)
Site I
b)
Aspartate transaminase
b)
Site II
c)
Alanine transaminase
c)
Site III
d)
Lactate dehydrogenase
d)
Site IV
Q.10 Glycine is required for the formation of all
Q.5
Factty liver is caused due to accumulation
of the following except:
of:
a)
Creatine
a)
Fatty acids
b)
Porphyrins
b)
Cholesterol
c)
Pyrimidines
c)
Phospholipids
d)
Glutathione
d)
Triacylglycerol
Q.11 Lipogenesis is decreased in all the
Q.6
Aspirin and indomethacin inhibit:
following except:
a)
Phospholipase A1
P.T.O.
a)
Restricted caloric intake
a)
Tyrosinemia
b)
High fat intake
b)
Alkaptonuria
c)
Deficiency of insulin
c)
Phenylketonuria
d)
High carbohydrate intake
d)
Homocystinuria
Q.12 Free glycerol cannot be used for
Q.20 Ciprofloxacin inhibits the synthesis of:
triglyceride synthesis in:
a)
DNA in prokaryotes
a)
Liver
b)
DNA in prokaryotes and eukaryotes
b)
Kidney
c)
RNA in prokaryotes
c)
Intestine
d)
RNA in prokaryotes and eukaryotes
d)
Adipose tissue
Q.13 Hypocholesterolemia can occur in:
a)
Hyperthyroidism
b)
Nephrotic syndrome
c)
Obstructive jaundice
d)
Diabetes Mellitus
Q.14 Congenital
absence
of
ornithine
transcarbamoylase causes:
a)
Hyperammonemia type I
b)
Hyperammonemia type II
c)
Hyperornithinemia
d)
Citrullinemia
Q.15 The nitrogen atoms of pyrimidine nucleus:
a)
Glutamate
b)
Glutamine
c)
Glutamate and Aspartate
d)
Glutamine and Aspartate
Q.16 Kernicterus can occur in:
a)
Retention hyperbilirubinemia
b)
Regurgitation hyperbilirubinemia
c)
Both of the above
d)
None of the above
Q.17 Rate limiting step fo glycolysis is catalyzed
by :
a)
Glucokinase
b)
Pyruvate kinase
c)
Phosphofructokinase-I
d)
Phosphohexose isomerase
Q.18 A
coenzyme
present
in
muscle
phosphorylase is:
a)
NAD
b)
Pyridoxal phosphate
c)
Thiamin pyrophosphate
d)
Coenzyme A
Q.19 Urinary excretion of homogentisic acid is
increased in:
This post was last modified on 17 February 2022