Download RTMNU (Rashtrasant Tukadoji Maharaj Nagpur University) B.Pharma (Bachelor of Pharmacy) 6th Semester 2017 Winter Pharmaceutics 6 Question Paper
B.Pharm. Sixth Semester (C.B.S.) Examination
PHARMACEUTICS?VI (Physical Pharmacy)
Paper?l
Time : Three Hours] [Maximum Marks : 80
NB. :? (1) Question No. 1 is compulsory.
(2) Solve any four questions from remaining.
(3) Draw neat labelled diagram wherever necessary.
(4) Assume suitable data wherever necessary.
1. Solve any five of the following : 4X5=20
(a) Why addition of sodium oleate to phenol water system lowers the critical solution
temperature ?
(b) De?ne glass transition temperature (Tg). Explain effect of cross linking on Tg of polymer.
(c) What is active and passive diffusion ? What is osmosis and ultra?ltration ?
(d) De?ne solubility according to LP.
(e) De?ne rate, order and molecularity of a reaction. What do you understand by pseudo?order
reaction ?
(i) What are bulges and spurs in the hysteresis loop ?
(g) What are complexes ? Give one example.
2. Derive an equation for solubility of non-ionic solids in liquids. 15
3. Explain steady state diffusion and derive Ficks First and Second law of diffusion. Add a note on
measurement of diffusion coef?cient. 15
4. What are Non-Newtonian systems ? Explain their types and comment brie?y on thixotropy. 15
5. (a) What is the in?uence of pH on solubility of weak acids and weak bases ? 8
(b) Give applications of polymers in Drug delivery systems. 7
6. (a) Write principle, working, disadvantages and modi?cations of Cup and Bob viscometer. 8
(b) Explain metal ion complexes. 7
7. (a) How the stoichiometric ratio and stability constant is determined by solubility and distribution
method ? 8
(b) How the half-life and shelf?life of drugs can be calculated ? 7
POY?2569 1
This post was last modified on 19 January 2020