Download RTMNU B.Pharma 7th Semester 2017 Winter Pharmaceutical Analysis 3 (Separation Techniques) Question Paper

Download RTMNU (Rashtrasant Tukadoji Maharaj Nagpur University) B.Pharma (Bachelor of Pharmacy) 7th Semester 2017 Winter Pharmaceutical Analysis 3 (Separation Techniques) Question Paper

NRJ/KW/17/4293
B.Pharm. Seventh Semester (C.B.S.) Examination
PHARMACEUTICAL ANALYSIS?III (Separation Techniques)
Paper?3
Time : Three Hours] [Maximum Marks : 80
NB. :? (1) Question N0. 1 is compulsory.
(2) Attempt any four questions out of remaining.
(3) Draw neat labelled diagram wherever necessary.
(4) Discuss the reaction, mechanism wherever necessary.
1. Solve any five questions :
(a) Differentiate between column chromatography and HPLC.
(b) Justify batch extraction procedure is better than single extraction.
(c) Write about various pumps used in HPLC.
(d) Differentiate between TLC and HPTLC.
(e) Write about adsorption Isotherms.
(1) Explain various column development techniques. 4X5=20
2. Give the principle of paper chromatography. Describe paper development techniques and detection
of spots in paper chromatography. 15
3. Draw block diagram of Gas chromatograph. Explain various carrier gas and detectors used in Gas
chromatography. 1 5
4. Give the principle, instrumentation and applications of HPLC. 15
5. De?ne Ion exchanger and classify them. Give synthesis of various ion-exchangers and applications of
ion-exchange chromatography. 15
6. Explain liq-liquid extraction techniques. Describe in detail counter current distribution and its applications.
15
7. Write notes on (any three) :
(a) HPTLC
(b) Electrophoresis
(c) Rate theory of chromatography
((1) Preparation of plates and application of spots in TLC. 5X3
POY?27560